Propoxyphene - PPX

Propoxyphene PPX


Screening Cut-off: 300 ng/ml
DEA Drug Class: Narcotic
Type: Prescription Drug
Trade Names: Darvon, Darvon-N
Street Names: Pain Killer

Drug Information

Propoxyphene (PPX) is a drug often prescribed to treat pain and is related structurally to methadone. Propoxyphene is generally taken orally and its effects peak in 1 – 2 hours. Overdose of propoxyphene effects the brain and can cause severe euphoria. Extended use of propoxyphene can cause respiratory depression, analgesia, stupor, and coma.

Drug Enforcement Agency (DEA) Drug Classification and Effects Information

  • Classification/Schedule IV: Prolonged use of these drugs may lead to limited physical or psychological dependency; lower abuse potential than schedule III
  • Physical Dependency: High-Low
  • Psychological Dependency: High-Low
  • Tolerance: Yes
  • Possible Effects: Euphoria, drowsiness, respiratory depression, constricted pupils, nausea
  • Effects of Overdose: Slow and shallow breathing, clammy skin, convulsions, coma, possible death
  • Withdrawal Syndrome: Watery eyes, runny nose, yawning, loss of appetite, irritability, tremors, panic, cramps, nausea, chills and sweating