Ecstasy - Methylenedioxymethamphetamine - MDMA

Ecstasy Methylenedioxymethamphetamine MDMA


Screening Cut-off: 500 ng/ml
DEA Drug Class: Hallucinogen
Type: Illicit Drug
Street Names: Adam, Bean, Disco Biscuit, E, Ecstasy, Eve, Go, Hug Drug, MBDB, MDA, MDEA, MDMA, X, Xtc, Adam, Decadence, Domex, E, Eve, Kleenex, Love Drug, M&M, Roll, Shabu, Triple Stacks, X, X-Tc

Drug Information

Methylenedioxymethamphetamine or Ecstasy (MDMA) is a designer drug first synthesized in 1914 by a German drug company for the treatment of obesity. Those who take the drug frequently report adverse effects, such as increased muscle tension and sweating. MDMA is not clearly a stimulant, although it has, in common with amphetamine drugs, a capacity to increase blood pressure and heart rate. MDMA does produce some perceptual changes in the form of increased sensitivity to light, difficulty in focusing, and blurred vision in some users. Its mechanism of action is thought to be via release of the neurotransmitter serotonin. MDMA may also release dopamine, although the general opinion is that this is a secondary effect of the drug (Nichols and Oberlender, 1990). The most pervasive effect of MDMA, occurring in virtually all people who took a reasonable dose of the drug, was to produce a clenching of the jaws.

Drug Enforcement Agency (DEA) Drug Classification and Effects Information

  • Classification/Schedule I: Illicit drugs with no medical use; high potential for abuse
  • Physical Dependency: None
  • Psychological Dependency: Moderate
  • Tolerance: Yes
  • Possible Effects: Heightened senses, teeth grinding and dehydration
  • Effects of Overdose: Increased body temperature, electrolyte imbalance, cardiac arrest
  • Withdrawal Syndrome: Muscle aches, drowsiness, depression, acne