Propoxyphene PPX

Screening Cut-off: 300 ng/ml
DEA Drug Class: Narcotic
Type: Prescription Drug
Trade Names: Darvon, Darvon-N
Street Names: Pain Killer

Drug Information

Propoxyphene (PPX) is a drug often prescribed to treat pain and is related structurally to methadone. Propoxyphene is generally taken orally and its effects peak in 1 – 2 hours. Overdose of propoxyphene effects the brain and can cause severe euphoria. Extended use of propoxyphene can cause respiratory depression, analgesia, stupor, and coma.

Drug Enforcement Agency (DEA) Drug Classification and Effects Information

• Classification/Schedule IV: Prolonged use of these drugs may lead to limited physical or psychological dependency; lower abuse potential than schedule III
• Physical Dependency: High-Low
• Psychological Dependency: High-Low
• Tolerance: Yes
• Possible Effects: Euphoria, drowsiness, respiratory depression, constricted pupils, nausea
• Effects of Overdose: Slow and shallow breathing, clammy skin, convulsions, coma, possible death
• Withdrawal Syndrome: Watery eyes, runny nose, yawning, loss of appetite, irritability, tremors, panic, cramps, nausea, chills and sweating

Resources

• Drug Information Chart

• DEA Chart Drugs of Abuse, Uses and Effects
• DEA Drug Classes
• DEA Drugs and Chemicals of Concern
• DEA Propoxyphene, Narcotics Information
• Getting High on Prescription Drugs PDF
• NIDA – Prescription Medication Information
• NIDA – Propoxyphene – Prescription Drug Abuse Report
• NIDA – Propoxyphene, Prescription and Over-the-Counter Medications Information
• NIDA – Propoxyphene, Prescription Medication Information
• NIDA Commonly Abused Drugs
• NIDA Prescription Drug Abuse Chart
• NIDA Prescription Drug Abuse Information PDF
• NLM/NIH: Prescription Drug Abuse Information
• Propoxyphene Drugs.com Information
• Propoxyphene Wikipedia Information
• Street Drug Information: Prescription Drug Abuse
• White House Information on: Prescription Drugs